Adding the equivalent of a miniature tornado to the interface between electrospray ionization (ESI) and a mass spectrometer (MS) has allowed researchers to improve the sensitivity and detection capability of the widely-used ESI-MS analytical technique. Among the scientific fields that could benefit from the new technique are proteomics, metabolomics and lipidomics – which serve biomedical and health applications ranging from biomarker detection and diagnostics to drug discovery and molecular medicine.
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